ALZHEIMER DRUG REVIEW

CONSUMER REPORTS EVALUATES 3 AVAILABLE DRUGS

There is no known cure for Alzheimer’s at the present time and no clear panacea with available drugs, however, there are drugs (some even used in combination) that have shown to slow the progression of AD.

Donepezil (Aricept) – for people with early-stage Alzheimer’s,

Galantamine (Razadyne) – for people with early-stage Alzheimer’s

Memantine (Namenda) – for people with middle-stage and late-stage Alzheimer’s

Aricept and Razadyne lower risk of adverse effects and offer higher tolerability, justifying their choice.

We chose Namenda (said the report) because it was the only drug approved by the FDA to treat people with middle to late-stage AD. This drug acts differently in the body. When used in combination Namenda offers an advantageous approach.

 TWO OF THE NEWEST DRUGS  (Post Consumer Report Review)

Among the newest drug candidates offering hope are EXELON (Rivastigmine).  This drug is believed to improve the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah-see-til-KO-leen). It is reported that people with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning. Rivastigmine is used to treat mild to moderate dementia caused by Alzheimer’s or Parkinson’s disease. The second drug in the pipeline moving toward approval is FLURIZAN (Tarenflurbil), an investigational drug being studied in patients with mild Alzheimer’s disease. It reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells. It is an accepted fact, amyloid plaques inflame, starving the brain of blood flow and oxygen.  A new study appearing in the Proceedings of the National Academy of Sciences builds on earlier study information that the age old herb turmeric (curcumin) could help slow or inhibit amyloid plaque formation. 

 

OMEGA 3 AND TURMERIC, MAJOR PROTECTION

For almost ten years I have stressed in my books and media interviews the benefits of two powerful natural inflammation fighters beneficial for many diseases including heart disease. Several years ago when researchers traveled to India to learn why that country had the lowest incidence of dementia and AD in the world, they determined the population’s diet of curry a (byproduct of the herb turmeric) was the reason.  “A chemical found in curry may help the immune system clear away brain plaques associated with Alzheimer’s disease.”This according to researchers from the David Geffen School of Medicine in Los Angeles and the Human BioMolecular Research Institute in San Diego, CA. found in The Proceedings of the National Academy of Sciences.

 Robert Friedland, M.D. of Case Western Reserve University School of Medicine in Cleveland, Ohio, said, a healthy diet containing fish could help ward off Alzheimer’s. Another study published in Archives of Neurology showed that people who ate Omega 3 rich fish, such as salmon, once a week, had a 60% lower risk of Alzheimer’s.

BY CONSUMER REPORTS